NOTE THAT IN THE ALIGNMENTS BELOW, GAPS MOST LIKELY INDICATE
RESIDUES MISSING IN THE ELECTRON DENSITY.
Alignment: 4GXU_M against 4GXV_H
Length=231
Length=231
Score = 473 bits (1218), Expect = 2e-175, Method: Compositional matrix adjust.
Identities = 231/231 (100%), Positives = 231/231 (100%), Gaps = 0/231 (0%)
Query 1 EVQLVQSGGGVVQPRRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGRNKYY 60
EVQLVQSGGGVVQPRRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGRNKYY
Sbjct 1 EVQLVQSGGGVVQPRRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGRNKYY 60
Query 61 ADSVKGRFTVSRDNSKNTLYLQMNSLRAEDTSVYYCARELLMDYYDHIGYSPGPTWGQGT 120
ADSVKGRFTVSRDNSKNTLYLQMNSLRAEDTSVYYCARELLMDYYDHIGYSPGPTWGQGT
Sbjct 61 ADSVKGRFTVSRDNSKNTLYLQMNSLRAEDTSVYYCARELLMDYYDHIGYSPGPTWGQGT 120
Query 121 LVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFP 180
LVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFP
Sbjct 121 LVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFP 180
Query 181 AVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDK 231
AVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDK
Sbjct 181 AVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDK 231
Alignment: 4GXU_N against 4GXV_L
Length=217
Length=217
Score = 437 bits (1125), Expect = 7e-162, Method: Compositional matrix adjust.
Identities = 217/217 (100%), Positives = 217/217 (100%), Gaps = 0/217 (0%)
Query 1 EPVLTQPPSASGSPGQRVTISCSGSSSNIGSYTVNWYQQLPGTAPKLLIYSLNQRPSGVP 60
EPVLTQPPSASGSPGQRVTISCSGSSSNIGSYTVNWYQQLPGTAPKLLIYSLNQRPSGVP
Sbjct 1 EPVLTQPPSASGSPGQRVTISCSGSSSNIGSYTVNWYQQLPGTAPKLLIYSLNQRPSGVP 60
Query 61 DRFSGSKSGTSASLAISGLQSEDEAVYYCAAWDDSLSAHVVFGGGTKLTVLGQPKAAPSV 120
DRFSGSKSGTSASLAISGLQSEDEAVYYCAAWDDSLSAHVVFGGGTKLTVLGQPKAAPSV
Sbjct 61 DRFSGSKSGTSASLAISGLQSEDEAVYYCAAWDDSLSAHVVFGGGTKLTVLGQPKAAPSV 120
Query 121 TLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAAS 180
TLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAAS
Sbjct 121 TLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAAS 180
Query 181 SYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 217
SYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
Sbjct 181 SYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 217
Alignment: 4GXU_A against 1RUZ_H
Length=331
Length=328
Score = 673 bits (1737), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 323/327 (99%), Positives = 324/327 (99%), Gaps = 0/327 (0%)
Query 1 ADPGDTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPLQLGKCN 60
A DTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPLQLGKCN
Sbjct 1 ATNADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPLQLGKCN 60
Query 61 IAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEELREQLSSVSSFEKFEI 120
IAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEELREQLSSVSSFEKFEI
Sbjct 61 IAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEELREQLSSVSSFEKFEI 120
Query 121 FPKTSSWPNHETTKGVTAACSYAGASSFYRNLLWLTKKGSSYPKLSKSYVNNKGKEVLVL 180
FPKTSSWPNHETTKGVTAACSYAGASSFYRNLLWLTKKGSSYPKLSKSYVNNKGKEVLVL
Sbjct 121 FPKTSSWPNHETTKGVTAACSYAGASSFYRNLLWLTKKGSSYPKLSKSYVNNKGKEVLVL 180
Query 181 WGVHHPPTGTDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVRDQAGRMNYYWTLLEP 240
WGVHHPPTGTDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVRDQAGRMNYYWTLLEP
Sbjct 181 WGVHHPPTGTDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVRDQAGRMNYYWTLLEP 240
Query 241 GDTITFEATGNLIAPWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIH 300
GDTITFEATGNLIAPWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIH
Sbjct 241 GDTITFEATGNLIAPWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIH 300
Query 301 PVTIGECPKYVRSTKLRMATGLRNIPS 327
PVTIGECPKYVRSTKLRMATGLRNIP+
Sbjct 301 PVTIGECPKYVRSTKLRMATGLRNIPA 327
Alignment: 4GXU_B against 1RUZ_I
Length=176
Length=160
Score = 333 bits (855), Expect = 2e-122, Method: Compositional matrix adjust.
Identities = 160/160 (100%), Positives = 160/160 (100%), Gaps = 0/160 (0%)
Query 1 GLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITNKVNSVIEKMN 60
GLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITNKVNSVIEKMN
Sbjct 1 GLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITNKVNSVIEKMN 60
Query 61 TQFTAVGKEFNNLERRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVRNLYE 120
TQFTAVGKEFNNLERRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVRNLYE
Sbjct 61 TQFTAVGKEFNNLERRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVRNLYE 120
Query 121 KVKSQLKNNAKEIGNGCFEFYHKCDDACMESVRNGTYDYP 160
KVKSQLKNNAKEIGNGCFEFYHKCDDACMESVRNGTYDYP
Sbjct 121 KVKSQLKNNAKEIGNGCFEFYHKCDDACMESVRNGTYDYP 160
Alignment: 4GXU_E against 1RUZ_J
Length=331
Length=328
Score = 673 bits (1737), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 323/327 (99%), Positives = 324/327 (99%), Gaps = 0/327 (0%)
Query 1 ADPGDTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPLQLGKCN 60
A DTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPLQLGKCN
Sbjct 1 ATNADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPLQLGKCN 60
Query 61 IAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEELREQLSSVSSFEKFEI 120
IAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEELREQLSSVSSFEKFEI
Sbjct 61 IAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEELREQLSSVSSFEKFEI 120
Query 121 FPKTSSWPNHETTKGVTAACSYAGASSFYRNLLWLTKKGSSYPKLSKSYVNNKGKEVLVL 180
FPKTSSWPNHETTKGVTAACSYAGASSFYRNLLWLTKKGSSYPKLSKSYVNNKGKEVLVL
Sbjct 121 FPKTSSWPNHETTKGVTAACSYAGASSFYRNLLWLTKKGSSYPKLSKSYVNNKGKEVLVL 180
Query 181 WGVHHPPTGTDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVRDQAGRMNYYWTLLEP 240
WGVHHPPTGTDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVRDQAGRMNYYWTLLEP
Sbjct 181 WGVHHPPTGTDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVRDQAGRMNYYWTLLEP 240
Query 241 GDTITFEATGNLIAPWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIH 300
GDTITFEATGNLIAPWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIH
Sbjct 241 GDTITFEATGNLIAPWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIH 300
Query 301 PVTIGECPKYVRSTKLRMATGLRNIPS 327
PVTIGECPKYVRSTKLRMATGLRNIP+
Sbjct 301 PVTIGECPKYVRSTKLRMATGLRNIPA 327
Alignment: 4GXU_F against 1RUZ_K
Length=176
Length=160
Score = 333 bits (855), Expect = 2e-122, Method: Compositional matrix adjust.
Identities = 160/160 (100%), Positives = 160/160 (100%), Gaps = 0/160 (0%)
Query 1 GLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITNKVNSVIEKMN 60
GLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITNKVNSVIEKMN
Sbjct 1 GLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITNKVNSVIEKMN 60
Query 61 TQFTAVGKEFNNLERRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVRNLYE 120
TQFTAVGKEFNNLERRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVRNLYE
Sbjct 61 TQFTAVGKEFNNLERRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVRNLYE 120
Query 121 KVKSQLKNNAKEIGNGCFEFYHKCDDACMESVRNGTYDYP 160
KVKSQLKNNAKEIGNGCFEFYHKCDDACMESVRNGTYDYP
Sbjct 121 KVKSQLKNNAKEIGNGCFEFYHKCDDACMESVRNGTYDYP 160
Alignment: 4GXU_C against 1RUZ_L
Length=331
Length=328
Score = 673 bits (1737), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 323/327 (99%), Positives = 324/327 (99%), Gaps = 0/327 (0%)
Query 1 ADPGDTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPLQLGKCN 60
A DTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPLQLGKCN
Sbjct 1 ATNADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPLQLGKCN 60
Query 61 IAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEELREQLSSVSSFEKFEI 120
IAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEELREQLSSVSSFEKFEI
Sbjct 61 IAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEELREQLSSVSSFEKFEI 120
Query 121 FPKTSSWPNHETTKGVTAACSYAGASSFYRNLLWLTKKGSSYPKLSKSYVNNKGKEVLVL 180
FPKTSSWPNHETTKGVTAACSYAGASSFYRNLLWLTKKGSSYPKLSKSYVNNKGKEVLVL
Sbjct 121 FPKTSSWPNHETTKGVTAACSYAGASSFYRNLLWLTKKGSSYPKLSKSYVNNKGKEVLVL 180
Query 181 WGVHHPPTGTDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVRDQAGRMNYYWTLLEP 240
WGVHHPPTGTDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVRDQAGRMNYYWTLLEP
Sbjct 181 WGVHHPPTGTDQQSLYQNADAYVSVGSSKYNRRFTPEIAARPKVRDQAGRMNYYWTLLEP 240
Query 241 GDTITFEATGNLIAPWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIH 300
GDTITFEATGNLIAPWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIH
Sbjct 241 GDTITFEATGNLIAPWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIH 300
Query 301 PVTIGECPKYVRSTKLRMATGLRNIPS 327
PVTIGECPKYVRSTKLRMATGLRNIP+
Sbjct 301 PVTIGECPKYVRSTKLRMATGLRNIPA 327
Alignment: 4GXU_D against 1RUZ_M
Length=176
Length=160
Score = 333 bits (855), Expect = 2e-122, Method: Compositional matrix adjust.
Identities = 160/160 (100%), Positives = 160/160 (100%), Gaps = 0/160 (0%)
Query 1 GLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITNKVNSVIEKMN 60
GLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITNKVNSVIEKMN
Sbjct 1 GLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAIDGITNKVNSVIEKMN 60
Query 61 TQFTAVGKEFNNLERRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVRNLYE 120
TQFTAVGKEFNNLERRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVRNLYE
Sbjct 61 TQFTAVGKEFNNLERRIENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVRNLYE 120
Query 121 KVKSQLKNNAKEIGNGCFEFYHKCDDACMESVRNGTYDYP 160
KVKSQLKNNAKEIGNGCFEFYHKCDDACMESVRNGTYDYP
Sbjct 121 KVKSQLKNNAKEIGNGCFEFYHKCDDACMESVRNGTYDYP 160