This benchmark case is special. Because the alignments below
align only the residues visible in the
electron densities, you cannot see that there is a stretch of 10
residues missing in BOTH bound and unbound
structures 1F34_B and
1F32_A. We recommend modeling them in for best docking
results.
NOTE THAT IN THE ALIGNMENTS BELOW, GAPS MOST LIKELY INDICATE
RESIDUES MISSING IN THE ELECTRON DENSITY.
Alignment: 1F34_A against 4PEP_
Query=
(325 letters)
>4PEP_
Length = 326
Score = 654 bits (1686), Expect = 0.0
Identities = 324/326 (99%), Positives = 325/326 (99%), Gaps = 1/326 (0%)
Query: 1 IGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDD 60
IGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDD
Sbjct: 1 IGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDD 60
Query: 61 SSTFEAT-QELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGI 119
SSTFEAT QELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGI
Sbjct: 61 SSTFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGI 120
Query: 120 LGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLN 179
LGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLN
Sbjct: 121 LGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLN 180
Query: 180 WVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASEN 239
WVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASEN
Sbjct: 181 WVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASEN 240
Query: 240 SDGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWI 299
SDGEMVISCSSIDSLPDIVFTI+GVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWI
Sbjct: 241 SDGEMVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWI 300
Query: 300 LGDVFIRQYYTVFDRANNKVGLAPVA 325
LGDVFIRQYYTVFDRANNKVGLAPVA
Sbjct: 301 LGDVFIRQYYTVFDRANNKVGLAPVA 326
Alignment: 1F34_B against 1F32_A
Query=
(138 letters)
>1F32_A
Length = 127
Score = 264 bits (674), Expect = 4e-76
Identities = 127/137 (92%), Positives = 127/137 (92%), Gaps = 10/137 (7%)
Query: 2 FLFSMSTGPFICTVKDNQVFVANLPWTMLEGDDIQVGKEFAARVEDCTNVKHDMAPTCTK 61
FLFSMSTGPFICTVKDNQVFVANLPWTMLEGDDIQVGKEFAARVEDCTNVKHDMAPTCTK
Sbjct: 1 FLFSMSTGPFICTVKDNQVFVANLPWTMLEGDDIQVGKEFAARVEDCTNVKHDMAPTCTK 60
Query: 62 PPPFCGPQDMKMFNFVGCSVLGNKLFIDQKYVRDLTAKDHAEVQTFREKIAAFEEQQENQ 121
PPPFCGPQDMKMFNFVGCSVLGNKLFIDQKYVRDLTAKDHAEVQTFREKIAAFEEQ
Sbjct: 61 PPPFCGPQDMKMFNFVGCSVLGNKLFIDQKYVRDLTAKDHAEVQTFREKIAAFEEQ---- 116
Query: 122 PPAGGLSPPPPPSFCTV 138
SPPPPPSFCTV
Sbjct: 117 ------SPPPPPSFCTV 127