Ecotin is a symmetric inhibitor, so there are two "correct answers" to
this docking problem
NOTE THAT IN THE ALIGNMENTS BELOW, GAPS MOST LIKELY INDICATE
RESIDUES MISSING IN THE ELECTRON DENSITY.
Alignment: 1EZU_C against 1TRM_A
Query=
(223 letters)
>1TRM_A
Length = 223
Score = 469 bits (1207), Expect = e-137
Identities = 222/223 (99%), Positives = 223/223 (99%)
Query: 1 IVGGYTCQENSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEG 60
IVGGYTCQENSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEG
Sbjct: 1 IVGGYTCQENSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEG 60
Query: 61 DEQFVNAAKIIKHPNFDRKTLNNNIMLIKLSSPVKLNARVATVALPSSCAPAGTQCLISG 120
+EQFVNAAKIIKHPNFDRKTLNNNIMLIKLSSPVKLNARVATVALPSSCAPAGTQCLISG
Sbjct: 61 NEQFVNAAKIIKHPNFDRKTLNNNIMLIKLSSPVKLNARVATVALPSSCAPAGTQCLISG 120
Query: 121 WGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDSCQGDSGGP 180
WGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDSCQGDSGGP
Sbjct: 121 WGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDSCQGDSGGP 180
Query: 181 VVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTIAAN 223
VVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTIAAN
Sbjct: 181 VVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTIAAN 223
Alignment: 1EZU_A against 1ECZ_A
Query=
(140 letters)
>1ECZ_A
Length = 142
Score = 283 bits (723), Expect = 9e-82
Identities = 138/140 (98%), Positives = 139/140 (98%)
Query: 1 SVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENK 60
SVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENK
Sbjct: 3 SVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENK 62
Query: 61 TLEGWGFPYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDN 120
TLEGWG+ YYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDN
Sbjct: 63 TLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDN 122
Query: 121 VDVKYRVWKAEEKIDNAVVR 140
VDVKYRVWKAEEKIDNAVVR
Sbjct: 123 VDVKYRVWKAEEKIDNAVVR 142
Alignment: 1EZU_B against 1ECZ_B
Query=
(140 letters)
>1ECZ_B
Length = 142
Score = 283 bits (723), Expect = 9e-82
Identities = 138/140 (98%), Positives = 139/140 (98%)
Query: 1 SVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENK 60
SVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENK
Sbjct: 3 SVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENK 62
Query: 61 TLEGWGFPYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDN 120
TLEGWG+ YYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDN
Sbjct: 63 TLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDN 122
Query: 121 VDVKYRVWKAEEKIDNAVVR 140
VDVKYRVWKAEEKIDNAVVR
Sbjct: 123 VDVKYRVWKAEEKIDNAVVR 142